Retinol Binding Protein-1 (RBP1)

• Gene Name:

  [RBP1]

• NCBI Gene ID:

  5950

• Reactivity:

  Human, Chimpanzee, Monkey, Goat, Rabbit, Rat, Mouse

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.

• Other Gene Names:

  [RBP4; RBP4; RDCCAS; MCOPCB10; PRBP; RBP]

• Short Name:

  [Retinol Binding Protein-1 (RBP1)]

• Other Product Names:

  [retinol-binding protein 4 isoform a; Retinol-binding protein 4; retinol-binding protein 4; retinol binding protein 4; Plasma retinol-binding protein]

• NCBI GI Number:

  55743122

• NCBI Accession Number:

  NP_006735.2

• NCBI GB Accession Number:

  NP_006735.2

• Uniprot Accession Number:

  P02753