Ornithine Decarboxylase-1 (ODC-1)

• Gene Name:

  [ODC-1]

• NCBI Gene ID:

  4953

• Reactivity:

  Human, Mouse, Rat

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

• Other Gene Names:

  [ODC1; ODC1; ODC; ODC]

• Short Name:

  [Ornithine Decarboxylase-1 (ODC-1)]

• Other Product Names:

  [ornithine decarboxylase isoform 1; Ornithine decarboxylase; ornithine decarboxylase; ornithine decarboxylase 1]

• NCBI GI Number:

  4505489

• NCBI Accession Number:

  NP_002530.1

• NCBI GB Accession Number:

  NP_002530.1

• Uniprot Accession Number:

  P11926