ROR2

CAT: 0544-MBS4381135-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381135-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[ROR2]
NCBI Gene ID
4920
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
ROR2 (receptor tyrosine kinase-like orphan receptor 2), also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2), is a single pass transmembrane tyrosine-protein kinase receptor. It contains a cytoplasmic tyrosine kinase domain, distally located serine-threonine-rich domains, an extracellular immunoglobulin-like domain, a cysteine-rich domain and a kringle domain. ROR2 is important for skeletal and endocrine development and is required for cartilage and growth plate development. It promotes the differentiation of osteoblasts and plays an important role in the early formation of chondrocytes. ROR2 sequesters and associates with Dlxin-1 affecting the transcriptional function of Msx-2. ROR2 also interacts with canoncial Wnt-1 and Wnt-3, regulating their signaling pathways. Defects in ROR2 can result in the autosomal dominant skeletal disorder, brachydactyly type B1, or the autosomal recessive skeletal disorder, Robinow syndrome.
Other Gene Names
[ROR2; ROR2; BDB; BDB1; NTRKR2; NTRKR2]
Short Name
[ROR2]
Other Product Names
[Tyrosine-protein kinase transmembrane receptor ROR2; Tyrosine-protein kinase transmembrane receptor ROR2; tyrosine-protein kinase transmembrane receptor ROR2; receptor tyrosine kinase like orphan receptor 2; Neurotrophic tyrosine kinase, receptor-related 2]
NCBI GI Number
90110767
NCBI Accession Number
Q01974.2
Uniprot Accession Number
Q01974

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