NGF-Receptor (p75)/CD271 (Soft Tissue Tumor Marker)

NGF-Receptor (p75)/CD271 (Soft Tissue Tumor Marker)

• Gene Name: [NGFR]
• NCBI Gene ID: 4804
• Reactivity: Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
• Other Gene Names: [NGFR; NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; TNFRSF16; NGF receptor]
• Short Name: [NGF-Receptor]
• Other Product Names: [tumor necrosis factor receptor superfamily member 16; Tumor necrosis factor receptor superfamily member 16; tumor necrosis factor receptor superfamily member 16; nerve growth factor receptor; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD]
• NCBI GI Number: 4505393
• NCBI Accession Number: NP_002498.1
• NCBI GB Accession Number: NP_002498.1
• Uniprot Accession Number: P08138