Ep-CAM/CD326 (Extracellular Domain) (Epithelial Marker)

Ep-CAM/CD326 (Extracellular Domain) (Epithelial Marker)

• Gene Name: [Ep-CAM/CD326]
• NCBI Gene ID: 4072
• Reactivity: Human
  Does not react with Mouse or Rat.
• Storage Conditions: Antibody with azide: store at 4 to 8 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Recognizes a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
• Other Gene Names: [EPCAM; EPCAM; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1; Ep-CAM; EGP; EGP314; hEGP314]
• Short Name: [Ep-CAM/CD326]
• Other Product Names: [epithelial cell adhesion molecule; Epithelial cell adhesion molecule; epithelial cell adhesion molecule; epithelial cell adhesion molecule; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; EGP; Epithelial glycoprotein 314; EGP314; hEGP314; KS 1/4 antigen; KSA; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1]
• NCBI GI Number: 218505670
• NCBI Accession Number: NP_002345.2
• NCBI GB Accession Number: NP_002345.2
• Uniprot Accession Number: P16422