Serum Amyloid P/APCS

Serum Amyloid P/APCS

• Gene Name: [APCS]
• NCBI Gene ID: 325
• Reactivity: Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer s disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation.
• Other Gene Names: [APCS; APCS; SAP; PTX2; HEL-S-92n; PTX2; SAP]
• Short Name: [Serum Amyloid P/APCS]
• Other Product Names: [serum amyloid P-component; Serum amyloid P-component; serum amyloid P-component; amyloid P component, serum; 9.5S alpha-1-glycoprotein]
• NCBI GI Number: 4502133
• NCBI Accession Number: NP_001630.1
• NCBI GB Accession Number: NP_001630.1
• Uniprot Accession Number: P02743