Gelsolin/Actin-depolymerizing Factor

CAT: 0544-MBS4380961-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4380961-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Gene Name
[GSN]
NCBI Gene ID
2934
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Gelsolin (also known as brevin, Actin-depolymerizing factor or ADF), a proteinof leukocytes, platelets and other cells, severs Actin filaments in thepresence of submicromolar calcium, thereby isolating cytoplasmic Actin gels. It is a calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. Defects in GSN are the cause of amyloidosis type 5 (AMYL5); also known as familial amyloidosis Finnish type, typically characterized by cranial neuropathy and lattice corneal dystrophy. Severe systemic disease can develop in some individuals causing peripheral polyneuropathy, amyloid cardiomyopathy, and nephrotic syndrome leading to renal failure.
Other Gene Names
[GSN; GSN; ADF; AGEL; ADF]
Short Name
[Gelsolin/Actin-depolymerizing Factor]
Other Product Names
[Gelsolin; Gelsolin; gelsolin; gelsolin; AGEL; Actin-depolymerizing factor; ADF; Brevin]
NCBI GI Number
121116
NCBI Accession Number
P06396.1
Uniprot Accession Number
P06396

Related Products

CatalogName
MBS6013551-01GSN, NT (GSN, Gelsolin, AGEL, Actin-depolymerizing factor, Brevin)
MBS6002384-01GSN, NT (GSN, Gelsolin, AGEL, Actin-depolymerizing factor, Brevin)
MBS625433-01Gelsolin (GSN, Actin Depolymerizing Factor, ADF, AGEL, Amyloidosis Finnish Type, Brevin, DKFZp313L0718)
MBS1031254-01Recombinant Brassica napus Actin-depolymerizing factor
MBS1440774-01Recombinant Vitis vinifera Actin-depolymerizing factor
MBS1092572-01Recombinant Lilium longiflorum Actin-depolymerizing factor
MBS6477681-01Gelsolin (GSN, Actin Depolymerizing Factor, ADF, AGEL, Amyloidosis Finnish Type, Brevin, DKFZp313L0718) (Biotin)
MBS6477689-01Gelsolin (GSN, Actin Depolymerizing Factor, ADF, AGEL, Amyloidosis Finnish Type, Brevin, DKFZp313L0718) (PE)
MBS6477679-01Gelsolin (GSN, Actin Depolymerizing Factor, ADF, AGEL, Amyloidosis Finnish Type, Brevin, DKFZp313L0718) (AP)
MBS6477680-01Gelsolin (GSN, Actin Depolymerizing Factor, ADF, AGEL, Amyloidosis Finnish Type, Brevin, DKFZp313L0718) APC

Alternative Products

CatalogName
318105-01Gelsolin (Actin Depolymerizing Factor, Actin-depolymerizing Factor, ADF, AGEL, Brevin, GSN)
303328Gelsolin (Actin Depolymerizing Factor, Actin-depolymerizing Factor, ADF, AGEL, Brevin, GSN) discontinued
144568Gelsolin (AGEL, ADF, Brevin, Actin-depolymerizing factor)
BNUM2239-50Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), 1mg/mL
BNUB2239-500Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), 0.2mg/mL
G2024-52GGelsolin (AGEL, Actin-depolymerizing Factor, ADF, Brevin, GSN)
223110-01GSN (Actin depolymerizing Factor, Actin-depolymerizing Factor, ADF, AGEL, Brevin, DKFZp313L0718, GELS_HUMAN, Gelsolin, GSN, ) discontinued
36-2433-100Anti-Gelsolin / Actin-depolymerizing Factor Monoclonal Antibody (Clone: CPTC-Gelsolin-1)
G2024-53LGelsolin (AGEL, Actin-depolymerizing Factor, ADF, Brevin, GSN) discontinued
031002GSN, NT (GSN, Gelsolin, AGEL, Actin-depolymerizing factor, Brevin)

Popular Products