FCGRT/FcRn (IgG Transporter)

• Gene Name:

  [FCGRT]

• NCBI Gene ID:

  2217

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.

• Other Gene Names:

  [FCGRT; FCGRT; FCRN; alpha-chain; FCRN; FcRn]

• Short Name:

  [FCGRT/FcRn]

• Other Product Names:

  [IgG receptor FcRn large subunit p51; IgG receptor FcRn large subunit p51; IgG receptor FcRn large subunit p51; Fc fragment of IgG receptor and transporter; IgG Fc fragment receptor transporter alpha chain; Neonatal Fc receptor]

• NCBI GI Number:

  209862839

• NCBI Accession Number:

  NP_001129491.1

• NCBI GB Accession Number:

  NP_001129491.1

• Uniprot Accession Number:

  P55899