Cadherin 17/LI Cadherin (Liver-Intestine Marker)

Cadherin 17/LI Cadherin (Liver-Intestine Marker)

• Gene Name: [CDH17]
• NCBI Gene ID: 1015
• Reactivity: Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: It recognizes a protein of 120kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
• Other Gene Names: [CDH17; CDH17; HPT1; CDH16; HPT-1; LI-cadherin]
• Short Name: [Cadherin 17/LI Cadherin]
• Other Product Names: [cadherin-17; Cadherin-17; cadherin-17; cadherin 17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin]
• NCBI GI Number: 221316595
• NCBI Accession Number: NP_001138135.1
• NCBI GB Accession Number: NP_001138135.1
• Uniprot Accession Number: Q12864