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Occludin (OCLN) (Tight Junctions Marker)

CAT: 0544-MBS4380767-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS4380767-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[OCLN]
NCBI Gene ID
100506658
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue; in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial Occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction.
Other Gene Names
[OCLN; OCLN; BLCPMG; PTORCH1; PPP1R115]
Short Name
[Occludin (OCLN)]
Other Product Names
[occludin isoform b; Occludin; occludin; occludin]
NCBI GI Number
327478416
NCBI Accession Number
NP_001192184.1
NCBI GB Accession Number
NP_001192184.1
Uniprot Accession Number
Q16625

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BNUM2183-50Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL
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36-2008-20Anti-Occludin (OCLN) (Tight Junctions Marker) Monoclonal Antibody (Clone:OCLN/2183)
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BNC042183-100Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF405S conjugate, 0.1mg/mL
BNC682183-500Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF568 conjugate, 0.1mg/mL
BNC742183-500Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF740 conjugate, 0.1mg/mL
BNCB2183-100Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), Biotin conjugate, 0.1mg/mL
BNC472183-500Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF647 conjugate, 0.1mg/mL
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