CD34 (Hematopoietic Stem Cell & Endothelial Marker)

CD34 (Hematopoietic Stem Cell & Endothelial Marker)

• Gene Name: [CD34]
• NCBI Gene ID: 947
• Reactivity: Human, Rat. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but shows low specificity.
• Other Gene Names: [CD34; CD34]
• Short Name: [CD34]
• Other Product Names: [hematopoietic progenitor cell antigen CD34 isoform a; Hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell antigen CD34; CD34 molecule; CD_antigen: CD34]
• NCBI GI Number: 68342038
• NCBI Accession Number: NP_001020280.1
• NCBI GB Accession Number: NM_001025109.1
• Uniprot Accession Number: P28906