CD6 (Negative Marker of T-regulatory Cells)

• Gene Name:

  [CD6]

• NCBI Gene ID:

  923

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

• Other Gene Names:

  [CD6; CD6; TP120]

• Short Name:

  [CD6]

• Other Product Names:

  [T-cell differentiation antigen CD6 isoform 2; T-cell differentiation antigen CD6; T-cell differentiation antigen CD6; CD6 molecule; T12; TP120; CD_antigen: CD6]

• NCBI GI Number:

  363543322

• NCBI Accession Number:

  NP_001241679.1

• NCBI GB Accession Number:

  NM_001254750.1

• Uniprot Accession Number:

  P30203