PMEPA1/TMEPAI (Tumor Suppressor Oncoprotein)

• Gene Name:

  [PMEPA1]

• NCBI Gene ID:

  56937

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

• Other Gene Names:

  [PMEPA1; STAG1; TMEPAI]

• Short Name:

  [PMEPA1/TMEPAI]

• Other Product Names:

  [protein TMEPAI; prostate transmembrane protein, androgen induced 1]

• Uniprot Accession Number:

  Q96W9