Neurofilament (NF-L) (Neuronal Marker)

Neurofilament (NF-L) (Neuronal Marker)

• Gene Name: [NF-L]
• NCBI Gene ID: 4747
• Reactivity: Human, Rat, Pig, Cow, Chicken. Others not known.
• Storage Conditions: Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: This MAb reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
• Other Gene Names: [NEFL; NEFL; NFL; NF-L; NF68; CMT1F; CMT2E; CMTDIG; PPP1R110; NF68; NFL; NF-L]
• Short Name: [Neurofilament (NF-L)]
• Other Product Names: [neurofilament light polypeptide; Neurofilament light polypeptide; neurofilament light polypeptide; neurofilament light; 68 kDa neurofilament protein; Neurofilament triplet L protein]
• NCBI GI Number: 105990539
• NCBI Accession Number: NP_006149.2
• NCBI GB Accession Number: NM_006158.4
• Uniprot Accession Number: P07196