MTAP (Tumor Suppressor Marker)

CAT: 0544-MBS4380631-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4380631-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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Gene Name
[MTAP]
NCBI Gene ID
4507
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.
Other Gene Names
[MTAP; MTAP; BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86fus; HEL-249; MSAP; MTA phosphorylase]
Short Name
[MTAP]
Other Product Names
[S-methyl-5'-thioadenosine phosphorylase; S-methyl-5'-thioadenosine phosphorylase; S-methyl-5'-thioadenosine phosphorylase; methylthioadenosine phosphorylase; 5'-methylthioadenosine phosphorylaseUniRule annotationManual assertion according to rulesiHAMAP-Rule:MF_03155; MTA phosphorylaseUniRule annotationManual assertion according to rulesiHAMAP-Rule:MF_03155; MTAPUniRule annotationManual assertion according to rulesiHAMAP-Rule:MF_03155; MTAPaseUniRule annotationManual assertion according to rulesiHAMAP-Rule:MF_03155]
NCBI GI Number
47132622
NCBI Accession Number
NP_002442.2
NCBI GB Accession Number
NM_002451.3
Uniprot Accession Number
Q13126

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Alternative Products

CatalogName
RA0650-C1MTAP (Tumor Suppressor Marker) ; Clone MTAP/1813
BNUM3137-50MTAP (Tumor Suppressor Marker) (MTAP/3137R), 1mg/mL
BNUM1813-50MTAP (Tumor Suppressor Marker) (MTAP/1813), 1mg/mL
BNUB3137-100MTAP (Tumor Suppressor Marker) (MTAP/3137R), 0.2mg/mL
BNUB1813-500MTAP (Tumor Suppressor Marker) (MTAP/1813), 0.2mg/mL
36-2804-100Anti-MTAP (Tumor Suppressor Marker) Monoclonal Antibody (Clone: MTAP/1813)
36-2806-20Anti-MTAP (Tumor Suppressor Marker) Monoclonal Antibody (Clone: MTAP/3137R)
BNUM3646-50MTAP (Tumor Suppressor Marker) (rMTAP/1813), 1mg/mL
BNCB3137-100MTAP (Tumor Suppressor Marker) (MTAP/3137R), Biotin conjugate, 0.1mg/mL
BNC941813-100MTAP (Tumor Suppressor Marker) (MTAP/1813), CF594 conjugate, 0.1mg/mL

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