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Interleukin 10 (IL10) (Immunoregulation Marker)

CAT: 0544-MBS4380606-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS4380606-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[IL10]
NCBI Gene ID
3586
Reactivity
Human
Storage Conditions
Antibody without azide, store at -20 to -80°C.
Antibody is stable for 12 months.
Non-hazardous.
No MSDS required.
Specificity
Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
Other Gene Names
[IL10; IL10; CSIF; TGIF; GVHDS; IL-10; IL10A; IL-10; CSIF]
Short Name
[Interleukin 10 (IL10)]
Other Product Names
[interleukin-10; Interleukin-10; interleukin-10; interleukin 10; Cytokine synthesis inhibitory factor; CSIF]
NCBI GI Number
10835141
NCBI Accession Number
NP_000563.1
NCBI GB Accession Number
NM_000572.3
Uniprot Accession Number
P22301

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BNUM2651-50Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 1mg/mL
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BNC042651-100Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), CF405S conjugate, 0.1mg/mL
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