IL3RA/CD123 (Acute Myeloid Leukemia Marker)

• Gene Name:

  [IL3RA]

• NCBI Gene ID:

  3563

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

• Other Gene Names:

  [IL3RA; IL3RA; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra; IL3R; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA]

• Short Name:

  [IL3RA/CD123]

• Other Product Names:

  [interleukin-3 receptor subunit alpha isoform 2; Interleukin-3 receptor subunit alpha; interleukin-3 receptor subunit alpha; interleukin 3 receptor subunit alpha; CD_antigen: CD123]

• NCBI GI Number:

  391224440

• NCBI Accession Number:

  NP_001254642.1

• NCBI GB Accession Number:

  NM_001267713.1

• Uniprot Accession Number:

  P26951