14-3-3 Sigma/Stratifin

• Gene Name:

  [SFN]

• NCBI Gene ID:

  2810

• Reactivity:

  Human. Others not tested.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  SFN (stratifin) is a p53-induced tumor suppressor gene which is activated in response to DNA damage, causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast, lung, prostate, liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer.

• Other Gene Names:

  [SFN; SFN; YWHAS; HME1]

• Short Name:

  [14-3-3 Sigma/Stratifin]

• Other Product Names:

  [14-3-3 protein sigma; 14-3-3 protein sigma; 14-3-3 protein sigma; stratifin; Epithelial cell marker protein 1; Stratifin]

• NCBI GI Number:

  5454052

• NCBI Accession Number:

  NP_006133.1

• NCBI GB Accession Number:

  NM_006142.4

• Uniprot Accession Number:

  P31947