Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker)

• Gene Name:

  [AKR1B1]

• NCBI Gene ID:

  231

• Reactivity:

  Human. Others not tested.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  AKR1B1, also deisgnated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor.

• Other Gene Names:

  [AKR1B1; AKR1B1; AR; ADR; ALR2; ALDR1; ALDR1; AR]

• Short Name:

  [Aldo-keto Reductase Family 1 Member B1]

• Other Product Names:

  [aldose reductase isoform 1; Aldose reductase; aldose reductase; aldo-keto reductase family 1 member B; Aldehyde reductase; Aldo-keto reductase family 1 member B1]

• NCBI GI Number:

  4502049

• NCBI Accession Number:

  NP_001619.1

• NCBI GB Accession Number:

  NM_001628.3

• Uniprot Accession Number:

  P15121