Desmin (Muscle Cell Marker)
CAT:
544-MBS4380542-01
Size:
0.02 mg (With BSA & Azide at 0.2mg/mL)
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Desmin (Muscle Cell Marker)
- Gene Name: [DES]
- NCBI Gene ID: 1674
- Reactivity: Human, Rat, Hamster, Chicken. Others not known.
- Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required. - Specificity: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
- Other Gene Names: [DES; DES; CSM1; CSM2; CDCD3; CMD1F; LGMD1D; LGMD1E; LGMD2R]
- Short Name: [Desmin]
- Other Product Names: [desmin; Desmin; desmin; desmin]
- NCBI GI Number: 55749932
- NCBI Accession Number: NP_001918.3
- NCBI GB Accession Number: NM_001927.3
- Uniprot Accession Number: P17661