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Desmin (Muscle Cell Marker)

CAT: 0544-MBS4380542-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS4380542-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[DES]
NCBI Gene ID
1674
Reactivity
Human, Rat, Hamster, Chicken. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
Other Gene Names
[DES; DES; CSM1; CSM2; CDCD3; CMD1F; LGMD1D; LGMD1E; LGMD2R]
Short Name
[Desmin]
Other Product Names
[desmin; Desmin; desmin; desmin]
NCBI GI Number
55749932
NCBI Accession Number
NP_001918.3
NCBI GB Accession Number
NM_001927.3
Uniprot Accession Number
P17661

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