Cathepsin K (Marker)

• Gene Name:

  [CTSK]

• NCBI Gene ID:

  1513

• Reactivity:

  Human. Others not known

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

• Other Gene Names:

  [CTSK; CTSK; CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2; CTSO; CTSO2]

• Short Name:

  [Cathepsin K]

• Other Product Names:

  [cathepsin K preproprotein; Cathepsin K; cathepsin K; cathepsin K; Cathepsin O; Cathepsin O2; Cathepsin X]

• NCBI GI Number:

  4503151

• NCBI Accession Number:

  NP_000387.1

• NCBI GB Accession Number:

  NM_000396.3

• Uniprot Accession Number:

  P43235