CD79b (B-Cell Marker)

CD79b (B-Cell Marker)

• Gene Name: [CD79b]
• NCBI Gene ID: 974
• Reactivity: Human. Others not known.
• Storage Conditions: Store at -20°C to -80°C. Non-hazardous. No MSDS required.
• Specificity: CD79 (also designated Ig alpha/Ig beta) is a heterodimer composed of alpha chains, designated CD79A or MB-1, and beta chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
• Other Gene Names: [CD79B; CD79B; B29; IGB; AGM6; B29; IGB]
• Short Name: [CD79b]
• Other Product Names: [B-cell antigen receptor complex-associated protein beta chain isoform 1; B-cell antigen receptor complex-associated protein beta chain; B-cell antigen receptor complex-associated protein beta chain; CD79b molecule; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD_antigen: CD79b]
• NCBI GI Number: 11038674
• NCBI Accession Number: NP_000617.1
• NCBI GB Accession Number: NM_000626.3
• Uniprot Accession Number: P40259