TIMP2 (Tissue Inhibitor of Metalloproteinase 2)

• Gene Name:

  [TIMP2]

• NCBI Gene ID:

  7077

• Reactivity:

  Human. Others not known.

• Specificity:

  It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

• Other Gene Names:

  [TIMP2; TIMP2; DDC8; CSC-21K; TIMP-2]

• Short Name:

  [TIMP2 (Tissue Inhibitor of Metalloproteinase 2)]

• Other Product Names:

  [metalloproteinase inhibitor 2; Metalloproteinase inhibitor 2; metalloproteinase inhibitor 2; TIMP metallopeptidase inhibitor 2; CSC-21K; Tissue inhibitor of metalloproteinases 2; TIMP-2]

• NCBI GI Number:

  4507511

• NCBI Accession Number:

  NP_003246.1

• NCBI GB Accession Number:

  NM_003255.4

• Uniprot Accession Number:

  P16035