PTEN (Tumor Suppressor Oncoprotein)

• Gene Name:

  [PTEN]

• NCBI Gene ID:

  5728

• Reactivity:

  Human. Others not known.

• Specificity:

  PTEN (phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase) contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. It was identified as a tumor suppressor that is mutated in a large number of cancers, including sporadic brain, breast, kidney, and prostate cancers.

• Other Gene Names:

  [PTEN; PTEN; BZS; DEC; CWS1; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del; PTENbeta; MMAC1; TEP1]

• Short Name:

  [PTEN]

• Other Product Names:

  [phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTEN; Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatase and tensin homolog; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog]

• NCBI GI Number:

  73765544

• NCBI Accession Number:

  NP_000305.3

• NCBI GB Accession Number:

  NM_000314.6

• Uniprot Accession Number:

  P60484