TACSTD2/TROP2 (Epithelial Marker)

• Gene Name:

  [TACSTD2]

• NCBI Gene ID:

  4070

• Reactivity:

  Human. Others not known.

• Specificity:

  TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.

• Other Gene Names:

  [TACSTD2; TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; GA733-1; M1S1; TROP2]

• Short Name:

  [TACSTD2/TROP2]

• Other Product Names:

  [tumor-associated calcium signal transducer 2; Tumor-associated calcium signal transducer 2; tumor-associated calcium signal transducer 2; tumor associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1]

• NCBI GI Number:

  166795236

• NCBI Accession Number:

  NP_002344.2

• NCBI GB Accession Number:

  NM_002353.2

• Uniprot Accession Number:

  P09758