TACSTD2/TROP2 (Epithelial Marker)

TACSTD2/TROP2 (Epithelial Marker)

• Gene Name: [TACSTD2]
• NCBI Gene ID: 4070
• Reactivity: Human. Others not known.
• Specificity: TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
• Other Gene Names: [TACSTD2; TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; GA733-1; M1S1; TROP2]
• Short Name: [TACSTD2/TROP2]
• Other Product Names: [tumor-associated calcium signal transducer 2; Tumor-associated calcium signal transducer 2; tumor-associated calcium signal transducer 2; tumor associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1]
• NCBI GI Number: 166795236
• NCBI Accession Number: NP_002344.2
• NCBI GB Accession Number: NM_002353.2
• Uniprot Accession Number: P09758