CD3e (T-Cell Marker)

• Gene Name:

  [CD3e]

• NCBI Gene ID:

  916

• Reactivity:

  Human, Chimpanzee

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes the -chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

• Other Gene Names:

  [CD3E; CD3E; T3E; TCRE; IMD18; T3E]

• Short Name:

  [CD3e]

• Other Product Names:

  [T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; CD3e molecule; T-cell surface antigen T3/Leu-4 epsilon chain; CD_antigen: CD3e]

• NCBI GI Number:

  4502671

• NCBI Accession Number:

  NP_000724.1

• NCBI GB Accession Number:

  NM_000733.3

• Uniprot Accession Number:

  P07766