Cyclin A2 (S- & G2-phase Cyclin)

Cyclin A2 (S- & G2-phase Cyclin)

• Gene Name: [CCNA2]
• NCBI Gene ID: 890
• Reactivity: Human. Others not tested.
• Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: It recognizes a protein of 54kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk s) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk s. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase.
• Other Gene Names: [CCNA2; CCNA2; CCN1; CCNA; Cyclin-A]
• Short Name: [Cyclin A2]
• Other Product Names: [cyclin-A2; Cyclin-A2; cyclin-A2; cyclin A2; Cyclin A]
• NCBI GI Number: 4502613
• NCBI Accession Number: NP_001228.1
• NCBI GB Accession Number: NM_001237.4
• Uniprot Accession Number: P20248