PGP9.5/UchL1 (pan-Neuronal Marker)

PGP9.5/UchL1 (pan-Neuronal Marker)

• Gene Name: [PGP9.5]
• NCBI Gene ID: 7345
• Reactivity: Human, Rat. Shows a broad species reactivity.
• Storage Conditions: Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
• Other Gene Names: [UCHL1; UCHL1; NDGOA; PARK5; PGP95; SPG79; PGP9.5; Uch-L1; HEL-117; PGP 9.5; HEL-S-53; UCH-L1; PGP9.5]
• Short Name: [PGP9.5/UchL1]
• Other Product Names: [ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin C-terminal hydrolase L1; Neuron cytoplasmic protein 9.5; PGP 9.5; PGP9.5; Ubiquitin thioesterase L1]
• NCBI GI Number: 21361091
• NCBI Accession Number: NP_004172.2
• NCBI GB Accession Number: NM_004181.4
• Uniprot Accession Number: P09936