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Thrombomodulin/CD141 (Endothelial Cell Marker)

CAT: 0544-MBS4380251-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS4380251-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[THBD]
NCBI Gene ID
7056
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposis sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
Other Gene Names
[THBD; THBD; TM; THRM; AHUS6; BDCA3; CD141; THPH12; THRM; TM]
Short Name
[Thrombomodulin/CD141]
Other Product Names
[thrombomodulin; Thrombomodulin; thrombomodulin; thrombomodulin; Fetomodulin; CD_antigen: CD141]
NCBI GI Number
4507483
NCBI Accession Number
NP_000352.1
NCBI GB Accession Number
NM_000361.2
Uniprot Accession Number
P07204

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