IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker)

• Gene Name:

  [IGHG]

• NCBI Gene ID:

  3500

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 degree C.
  Antibody without azide - store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

• Other Gene Names:

  [IGHG1; IGHG1]

• Short Name:

  [IgG (Immunoglobulin Gamma Heavy Chain)]

• Other Product Names:

  [Immunoglobulin heavy constant gamma 1; Immunoglobulin heavy constant gamma 1; immunoglobulin heavy constant gamma 1 (G1m marker); Ig gamma-1 chain C region]

• NCBI GI Number:

  121039

• NCBI Accession Number:

  P01857.1

• Uniprot Accession Number:

  P01857