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FOXA1/HNF3A

CAT: 0544-MBS4380023-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4380023-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[FOXA1]
NCBI Gene ID
3169
Reactivity
Human, Rat. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.
Other Gene Names
[FOXA1; FOXA1; HNF3A; TCF3A; HNF3A; TCF3A; HNF-3-alpha; HNF-3A; TCF-3A]
Short Name
[FOXA1/HNF3A]
Other Product Names
[hepatocyte nuclear factor 3-alpha; Hepatocyte nuclear factor 3-alpha; hepatocyte nuclear factor 3-alpha; forkhead box A1; Forkhead box protein A1; Transcription factor 3A; TCF-3A]
NCBI GI Number
24497501
NCBI Accession Number
NP_004487.2
NCBI GB Accession Number
NM_004496.3
Uniprot Accession Number
P55317

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