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Quinpirole

CAT: 0804-HY-B1752Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B1752Size:1 Each
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Description
Quinpirole (LY 171555) is a dopamine D2/D3 receptor agonist with activity in reducing hypothalamic norepinephrine concentrations. The effects of Quinpirole are not produced by the selective D1 agonist SKF 38393 or the dextrorotatory isomer of Quinpirole, which lacks D2 agonist activity. By activating D2 receptors, Quinpirole leads to a decrease in dopamine metabolites, a decrease in hypothalamic norepinephrine concentrations, and a possible increase in MHPG sulfate by enhancing norepinephrine release[1].
CAS Number
80373-22-4
Product Name Alternative
LY 171555; (-) -LY 141865
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/quinpirole.html
Smiles
CCCN1[C@@]2([H])[C@@](CCC1)([H])CC3=C(C=NN3)C2
Molecular Formula
C13H21N3
Molecular Weight
219.33
References & Citations
[1]Decrease in hypothalamic epinephrine concentration and other neurochemical changes produced by quinpirole, a dopamine agonist, in rats
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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