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Mequinol

CAT: 0804-HY-30270-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-30270-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mequinol (4-Methoxyphenol) yes MercurialisOne of the bioactive ingredients, mainly used for skin discoloration[1]. MequinolIs an antioxidant that has additive/synergistic effects on carcinogenesis when combined with other phenolic antioxidants. Mequinolalso promote hERαDependent chaperone production with potential estrogenic activity[1][2][3].
CAS Number
150-76-5
Product Name Alternative
P-Hydroxyanisole
UNSPSC
12352005
Hazard Statement
H302, H317, H319, H361, H401, H412
Target
Estrogen Receptor/ERR; HSP
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/mequinol.html
Purity
99.98
Solubility
DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL
Smiles
OC(C=C1)=CC=C1OC
Molecular Formula
C7H8O2
Molecular Weight
124.14
Precautions
H302, H317, H319, H361, H401, H412
References & Citations
[1]Callender VD, et al. Postinflammatory hyperpigmentation: etiologic and therapeutic considerations. Am J Clin Dermatol. 2011 Apr 1;12 (2) :87-99.|[2]Kita K, et al. Increase in the levels of chaperone proteins by exposure to beta-estradiol, bisphenol A and 4-methoxyphenol in human cells transfected with estrogen receptor alpha cDNA. Toxicol In Vitro. 2009 Jun;23 (4) :728-35.|[3]Hirose M, et al. Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, 4-methoxyphenol and catechol at low doses, either alone or in combination, and modulation of their effects in a rat medium-term multi-organ carcinogenesis model. Carcinogenesis. 1998 Jan;19 (1) :207-12.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
Launched

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