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Raxibacumab

CAT: 0804-HY-P9957-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P9957-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Raxibacumab (ABthrax) is a human IgG1 monoclonal antibody against Bacillus anthracis protective antigen (PA) . Raxibacumab blocks the toxin’s deleterious effects by preventing binding of the protective antigen component of the anthrax toxin to its receptors in host cells, thereby blocking the toxin’s deleterious effects. Raxibacumab can be used for anti-anthrax research[1][2].
CAS Number
565451-13-0
Product Name Alternative
ABthrax
UNSPSC
12352203
Target
Bacterial
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/raxibacumab.html
Purity
98.88
Solubility
H2O
Smiles
[Raxibacumab]
Molecular Weight
(142.96 kDa)
References & Citations
[1]Mazumdar S. Raxibacumab. MAbs.2009 Nov-Dec;1 (6) :531-8. |[2]Kummerfeldt CE. Raxibacumab: potential role in the treatment of inhalational anthrax. Infect Drug Resist. 2014 Apr 29;7:101-9. |[3]Cui X, et.al. Late treatment with a protective antigen-directed monoclonal antibody improves hemodynamic function and survival in a lethal toxin-infused rat model of anthrax sepsis. J Infect Dis. 2005 Feb 1;191 (3) :422-34.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched

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