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Vilazodone

CAT: 0804-HY-14262-01Size: 5 mgDry Ice: NoHazardous: No
CAT#: HY-14262-01Size: 5 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vilazodone (EMD 68843; SB 659746A) is a potent, selective and orally active serotonin reuptake inhibitor (SSRI) and partial 5-HT1A receptor agonist. Vilazodone exhibits antidepressant efficacy in vivo can be used for the research of major depressive disorder (MDD) and affective disorders[1][2].
CAS Number
[163521-12-8]
Product Name Alternative
EMD 68843; SB659746A
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
5-HT Receptor; Serotonin Transporter
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vilazodone.html
Purity
99.83
Solubility
DMSO : 75 mg/mL (ultrasonic)
Smiles
NC(C1=CC2=C(C=CC(N3CCN(CCCCC4=CNC5=CC=C(C=C54)C#N)CC3)=C2)O1)=O
Molecular Formula
C26H27N5O2
Molecular Weight
441.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee A. Dawson et al. Vilazodone: A 5-HT1A Receptor Agonist/Serotonin Transporter Inhibitor for the Treatment of Affective Disorders CNS Neuroscience & Therapeutics Volume 15, Issue 2, pages 107-117, June 2009|[2]Cruz MP. Vilazodone HCl (Viibryd) : A Serotonin Partial Agonist and Reuptake Inhibitor For the Treatment of Major Depressive Disorder. P T. 2012 Jan;37 (1) :28-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT1 Receptor; mLAG-3
Citation 01
Arch Pharm (Weinheim) . 2024 May 30:e2400263.|Cell. 2025 Oct 24:S0092-8674 (25) 01131-6.|Nature. 2023 Dec;624 (7992) :672-681.|Prog Neuropsychopharmacol Biol Psychiatry. 2024 Mar 2:130:110911.|Mol Pharmacol. 2023 Nov;104 (5) :230-238.

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