Kasugamycin

• Description:

  Kasugamycin (Ksg) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation[1].

• Product Name Alternative:

  Ksg

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/kasugamycin.html

• Purity:

  99.82

• Solubility:

  H2O : 7 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O

• Molecular Formula:

  C14H25N3O9

• Molecular Weight:

  379.36

• References & Citations:

  [1]"Hong Zhang, et al. Simultaneous determination of kasugamycin and validamycin-A residues in cereals by consecutive solid-phase extraction combined with liquid chromatography-tandem mass spectrometry. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Mar;35 (3) :487-497. "

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  6980-18-3