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L-703606

CAT: 0804-HY-117216Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117216Size:1 Each
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Description
L-703606 is a potent, selective antagonist of NK1 receptor. L-703606 can be used for study of gastric acid secretion[1][2].
CAS Number
144425-84-3
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-703606.html
Smiles
IC(C=CC=C1)=C1CN[C@@H](C2CCN3CC2)[C@@H]3C(C4=CC=CC=C4)C5=CC=CC=C5
Molecular Formula
C27H29IN2
Molecular Weight
508.44
References & Citations
[1]Minowa S, et al. Role of neuropeptide receptor systems in vanilloid VR1 receptor-mediated gastric acid secretion in rat brain. Eur J Pharmacol. 2004;486 (3) :317-324.|[2]Francis BE, et al. Radioiodinated L-703,606: a potent, selective antagonist to the human NK1 receptor. Appl Radiat Isot. 1994;45 (1) :97-103.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported