Products for Research Use Only
RegisterLogin

Brilacidin

CAT: 0804-HY-19892-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-19892-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Brilacidin (PMX 30063) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin is a defensin mimetic antibiotic compound[1][2].
CAS Number
1224095-98-0
Product Name Alternative
PMX 30063
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Brilacidin.html
Purity
92.54
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC=NC(C(NC2=CC(C(F)(F)F)=CC(NC(CCCCNC(N)=N)=O)=C2O[C@H]3CNCC3)=O)=C1)NC4=CC(C(F)(F)F)=CC(NC(CCCCNC(N)=N)=O)=C4O[C@H]5CNCC5
Molecular Formula
C40H50F6N14O6
Molecular Weight
936.91
References & Citations
[1]Bruk Mensa , et al. Comparative Mechanistic Studies of Brilacidin, Daptomycin, and the Antimicrobial Peptide LL16. Antimicrob Agents Chemother. 2014 Sep;58 (9) :5136-45.|[2]Regis P Kowalski, et al. An Independent Evaluation of a Novel Peptide Mimetic, Brilacidin (PMX30063), for Ocular Anti-infective. J Ocul Pharmacol Ther. Jan-Feb 2016;32 (1) :23-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
BA1157-10Brilacidin
ZYB09599-01Brilacidin tetrahydrochloride
319690Brilacidin HCl
A20654-1Brilacidin 1mg
A20654-50Brilacidin 50mg
A20654-10Brilacidin 10mg
A20654-5Brilacidin 5mg
AR-B01984-01Brilacidin-15N4
CS-T-93677Brilacidin-15N4 Tetrahydrochloride

Popular Products