Valnoctamide

• Description:

  Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors[1].

• Product Name Alternative:

  Valmethamide

• UNSPSC:

  12352211

• Hazard Statement:

  H302

• Target:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/valnoctamide.html

• Concentration:

  10mM

• Purity:

  99.0

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  CCC(C(C(N)=O)CC)C

• Molecular Formula:

  C8H17NO

• Molecular Weight:

  143.23

• Precautions:

  H302

• References & Citations:

  [1]Spampanato J, et al. Valnoctamide enhances phasic inhibition: a potential target mechanism for the treatment of benzodiazepine-refractory status epilepticus. Epilepsia. 2014 Sep;55 (9) :e94-8.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 3

• CAS Number:

  [4171-13-5]