SingleFlowEx CD1a APC

• Description:

  SingleFlowEx is fluorochrome-labeled monoclonal antibody single reagent for use in laboratory-developed multicolor flow cytometry tests in order to examine human clinical samples. SingleFlowEx can be used in various multicolor combinations. Laboratory shall establish the SingleFlowEx performance characteristics in conjunction with other reagents in normal and pathological samples.

• Certification:

  RUO (GMP)

• Clone:

  SK9

• Applications:

  FC (QC tested)

• Concentration:

  0.10 mg/mL

• Format:

  APC

• Buffer:

  Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• Components:

  1 vial of monoclonal antibody reagent.The content (1 mL) is sufficient for min. 100 Tests.

• References & Citations:

  *Kader M, Smith AP, Guiducci C, Wonderlich ER, Normolle D, Watkins SC, Barrat FJ, Barratt-Boyes SM: Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection. PLoS Pathog. 2013;9 (7) :e1003530., URL: https://pubmed.ncbi.nlm.nih.gov/23935491/, *Awasthi S, Wolf R, White G: Ontogeny and phagocytic function of baboon lung dendritic cells. Immunol Cell Biol. 2009 Jul;87 (5) :419-27., URL: http://www.ncbi.nlm.nih.gov/pubmed/19223853 , *Tenca C, Merlo A, Zarcone D, Saverino D, Bruno S, De Santanna A, Ramarli D, Fabbi M, Pesce C, Deaglio S, Ciccone E, Malavasi F, Grossi CE: Death of T cell precursors in the human thymus: a role for CD38. Int Immunol. 2003 Sep;15 (9) :1105-16., URL: http://www.ncbi.nlm.nih.gov/pubmed/12917263 , *Brown KN, Trichel A, Barratt-Boyes SM: Parallel loss of myeloid and plasmacytoid dendritic cells from blood and lymphoid tissue in simian AIDS. J Immunol. 2007 Jun 1;178 (11) :6958-67., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=brown+kn+trichel+a , *Zimmer MI, Larregina AT, Castillo CM, Capuano S 3rd, Falo LD Jr, Murphey-Corb M, Reinhart TA, Barratt-Boyes SM: Disrupted homeostasis of Langerhans cells and interdigitating dendritic cells in monkeys with AIDS. Blood. 2002 Apr 15;99 (8) :2859-68., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=zimmer+mi+larregina+at+castillo+cm , *Wood GS, Burns BF, Dorfman RF, Warnke RA: The immunohistology of non-T cells in the acquired immunodeficiency syndrome. Am J Pathol. 1985 Sep;120 (3) :371-9., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=am+j+pathol+120+371, *Use of this product has not been published., URL:

• Storage Conditions:

  Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.