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MDK0734

CAT: 0804-HY-119467Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119467Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MDK0734 is a selective inhibitor that inhibits feline hepsin B endopeptidase and exopeptidase activities. MDK0734 demonstrated efficacy in a cell-based in vitro tumor invasion model, significantly attenuating the invasive ability of MCF-10A neoT cells. MDK0734 provides new potential inhibitors for the development of clinically useful compounds targeting the deleterious effects of feline hepsin B in cancer progression[1].
CAS Number
1366240-73-4
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdk0734.html
Smiles
O=[N+]([O-])C1=C2C=CC=NC2=C(C=C1)N3CCC(CC3)C
Molecular Formula
C15H17N3O2
Molecular Weight
271.31
References & Citations
[1]Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19197108-01MDK0734

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