IRS-1 (phospho-Ser318) rabbit pAb

• Background:

  This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]

• Description:

  This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],

• Synonyms:

  Insulin receptor substrate 1 (IRS-1)

• Gene ID:

  3667

• UniProt:

  P35568

• Cellular Locus:

  Nucleus,cytoplasm,cytosol,plasma membrane,insulin receptor complex,caveola,intracellular membrane-bounded organelle,

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized phosho peptide around human IRS-1 (Ser318)

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC

• Validated Applications:

  WB, IHC

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight:

  170kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  170 kD

• Subcellular Location:

  Nucleus, cytoplasm, cytosol, plasma membrane, insulin receptor complex, caveola, intracellular membrane-bounded organelle

• Other Product Names:

  Insulin receptor substrate 1 (IRS-1)

• Gene ID (Human):

  3667

• SwissProt (Human):

  P35568