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UT-A1 Antibody (APC)

CAT: 0013-GTR18029459Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18029459Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to UT-A1 (APC) . UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promoter and expressed in the thin descending limb of Henle, viz. UT-A2.) .
Product Name Alternative
UT-A1, UT-A2, UT1, UT2, UTA, UTA1, UT2_HUMAN, UT2, UTR, SLC14A2, Slc14a2, Solute carrier family 14 member 2, Solute carrier family 14 (urea transporter) member 2, Urea transporter, Urea transporter 2, Urea transporter kidney, HUT2, hUT-A6, FLJ16167, MGC119566, MGC119567, kidney
UniProt
Q62668
Reactivity
Mouse, Rat
Immunogen
Produced against a synthetic peptide mapped to the C-terminal tail (amino acids 911-929) of rat UT-A1 (antibody designation L194)
Target
UT-A1
Clonality
Polyclonal
Conjugation
APC
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purification
Peptide Affinity Purified
Concentration
1 mg/ml
Dilution
WB (1:1000) ; IHC (1:25)
Molecular Weight
97 and 127kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of UT-A1 in 20 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_062220
Host or Source
Rabbit
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Entrez
54302

UniProtKB · Q62668

Urea transporter 2

UT2_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
Q62668
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Slc14a2
Protein existence
1: Evidence at protein level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9R1Y7, Q9WTT8, Q9Z2R3
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

GlycoproteinPhosphoprotein

Technical term

Reference proteome

Domain

TransmembraneTransmembrane helix

Biological process

Transport

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