Nizatidine

CAT: 0804-HY-B0310-01Size: 1 gDry Ice: NoHazardous: No

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CAT#:0804-HY-B0310-01Size:1 g

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Description

Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models[1].

CAS Number

76963-41-2

UNSPSC

12352005

Hazard Statement

H302

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Nizatidine.html

Purity

99.68

Solubility

DMSO : ≥ 50 mg/mL|H2O : 20 mg/mL (ultrasonic)

Smiles

CN/C(NCCSCC1=CSC(CN(C)C)=N1)=C\[N+]([O-])=O

Molecular Formula

C12H21N5O2S2

Molecular Weight

331.46

Precautions

H302

References & Citations

[1]T M Lin, et al. Actions of nizatidine, a selective histamine H2-receptor antagonist, on gastric acid secretion in dogs, rats and frogs. J Pharmacol Exp Ther. 1986 Nov;239 (2) :406-10.|[2]Shen Li, et al. Abstract 4004: The H2 receptor antagonist nizatidine inhibits carcinogenesis in two rodent models of hepatocellular carcinoma. Tumor Biology. Cancer research.|[3]Ahmed S. Alazzouni, et al. Comparative histological and histochemical studies between ranitidine and nizatidine in treatment of peptic ulcer with evaluation of their adverse effects on male sex hormones. The Journal of Basic and Applied Zoology volume

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

H2 Receptor

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Nizatidine

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