Dehydrozingerone

• Description:

  Dehydrozingerone (Compound 10), a structural half analogue of Curcumin (HY-N0005), is a phenolic compound with antibacterial, anticancer, antioxidant, anti-Alzheimer’s and antifungal activity, which is isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone shows moderate inhibitory activities on the secretion of HBsAg in HepG 2 cells with an IC50 value of 0.50 mM[1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Bacterial; Fungal; HIV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dehydrozingerone.html

• Purity:

  99.98

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(/C=C/C1=CC=C(O)C(OC)=C1)=O

• Molecular Formula:

  C11H12O3

• Molecular Weight:

  192.21

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]He K, et al. Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens. J Asian Nat Prod Res. 2016 Jun;18 (6) :528-34.|[2]Kubra IR, et al. Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds. J Food Sci Technol. 2014 Feb;51 (2) :245-55.|[3]Song X, et al. Dehydrozingerone Inspired Discovery of Potential Broad-Spectrum Fungicidal Agents as Ergosterol Biosynthesis Inhibitors. J Agric Food Chem. 2019 Oct 16;67 (41) :11354-11363.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  RT, stored under nitrogen

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1080-12-2]