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KDEL Antibody (APC)

CAT: 0013-GTR18029219Size: 200 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18029219Size:200 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to KDEL (APC) . The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu) . Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER..
Product Name Alternative
KDEL, K-D-E-L, Lys-Asp-Glu-Leu, Lys-Asp-Glu-Leu (KDEL), Lysine-aspartic acid-glutamate-leucine
Reactivity
Human, Mouse, Rat
Immunogen
KDEL containing peptide immunogen
Target
KDEL
Clonality
Polyclonal
Conjugation
APC
Field of Research
Cell Biology, Disease Biomarkers, Protein Biochemistry, Signal Transduction
Purification
Protein A Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), ICC/IF (1:100)
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
A 1:1000 dilution was sufficient for detection of KDEL-containing proteins in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG as the secondary.
Tested Applications
ICC, IF, IHC, WB
Host or Source
Rabbit
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA

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