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QKI Antibody (APC)

CAT: 0013-GTR18029112Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18029112Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal to QKI (APC) . QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients..
Product Name Alternative
Protein quaking, Hqk, HqkI, KH Domain Containing, RNA Binding (QKI)
UniProt
Q96PU8
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical) . Rat: 99% identity (339/341 amino acids identical) > 90% identity with QKI-6, QKI-7 and QKI-7b.
Target
QKI
Clonality
Monoclonal
Clone
N147/6 (Formerly sold as S147-6)
Conjugation
APC
Field of Research
Stem Cell & Developmental Biology
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000)
Molecular Weight
36-38kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of Pan-QKI in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_006766.1
Host or Source
Mouse
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Isotype
IgG2b
Entrez
9444

UniProtKB · Q96PU8

KH domain-containing RNA-binding protein QKI

QKI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96PU8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
QKI
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q2I375, Q5MJQ1, Q969L9, Q96EJ3, Q96KA3, Q96PU6, Q96PU7, Q9P0X6, Q9P0X7, Q9P0X8, Q9P0X9, Q9P0Y0, Q9P0Y1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

Developmental proteinDNA-bindingRNA-binding

Biological process

DifferentiationmRNA processingmRNA splicingmRNA transportTranslation regulationTransport

PTM

MethylationPhosphoproteinUbl conjugation

Domain

SH3-binding

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