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FGF13 Antibody (HRP)

CAT: 0013-GTR18029049Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18029049Size:100 µg
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Description
Mouse monoclonal to FGFA (HRP) . FGF13 (Fibroblast growth factor 13), also called FHF2 is a protein that in humans is encoded by the FGF13 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF13is a large gene, extending over approximately 200 kb in Xq26. 3, and contains at least 7 exons. By cytogenetic, FISH, and database analysis, Gecz et al. (1999) localized the FGF13 gene within a 400-kb duplication interval on chromosome Xq26. 3. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene..
Product Name Alternative
FGF-13, FHF-2, FGF13, FHF2, Fibroblast growth factor homologous factor 2A, Fibroblast growth factor 13A, FGF13A
UniProt
Q92913
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide amino acids 2-18 (AAAIASSLIRQKRQARE) of human FHF2A. 100% identical to rat, 94% identical to mouse. > 80% identity with FGF12A/FHF1A, FGF14A/FHF4A and FGF11A/FHF3A.
Target
FGF13
Clonality
Monoclonal
Clone
N235/22
Conjugation
HRP
Field of Research
Neuroscience
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000)
Molecular Weight
30kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of FHF2A (FGF13) in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
AAH34340
Host or Source
Mouse
Preservative
73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide 0.23mM Citrate
Isotype
IgG2b
Entrez
2258

UniProtKB · Q92913

Fibroblast growth factor 13

FGF13_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92913
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FGF13
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
FGF-13
EC number
—
Processing
—
Secondary accessions
B1AK18, B7Z4M7, B7Z8N0, D3DWH4, O95830, Q9NZH9, Q9NZI0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCell projectionCytoplasmMembraneMicrotubuleNucleus

Disease

Disease variantEpilepsyIntellectual disability

Biological process

Neurogenesis

PTM

Phosphoprotein

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