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Alpha2C Adrenergic Antibody (APC)

CAT: 0013-GTR18028993Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18028993Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal to Alpha 2C Adrenergic R (APC) . The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein..
Product Name Alternative
Alpha-2C Adrenergic Receptor, Alpha-2C Adrenoceptor, Alpha-2C Adrenoreceptor, ADRA2C, ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR, Alpha2-AR-C4, Alpha2-C4, Adrenoceptor Alpha 2C, Adrenergic receptor alpha 2C
UniProt
P18825
Reactivity
Human, Mouse
Immunogen
Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor
Target
Alpha2C Adrenergic
Clonality
Monoclonal
Clone
N330A/80 (Formerly sold as S330A-80)
Conjugation
APC
Field of Research
Neuroscience, Signal Transduction
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000)
Molecular Weight
50kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of Alpha2C Adrenergic Receptor in 20 μg of COS cells transiently transfected with HA-tagged Alpha- lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, WB
NCBI Accession Number
NP_000674.2
Host or Source
Mouse
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Isotype
IgG1
Entrez
152

UniProtKB · P18825

Alpha-2C adrenergic receptor

ADA2C_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P18825
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADRA2C
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
P35369, Q9HB49
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

TransmembraneTransmembrane helix

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