Synaptotagmin 7 Antibody (APC)

Mouse monoclonal to Synaptotagmin-7 (APC) . Synaptotagmins constitute a family of membrane trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first domain mediates Ca (2+) -dependent phospholipid Synaptotagmins constitute a family of membrane trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first domain mediates Ca (2+) -dependent phospholipid.

IPCA-7, PCANAP7, Prostate cancer-associated protein 7, SYT-7, SYT7, Synaptotagmin 7, Synaptotagmin VII, SytVII

Q9R0N7

Human, Mouse, Rat

Fusion protein amino acids 150-239 (Cytoplasmic C2A domain) of mouse Synaptotagmin-7

Synaptotagmin 7

N275/14 (Formerly sold as S275-14)

APC

Disease Biomarkers, Neuroscience

Protein G Purified

1 mg/ml

WB (1:1000), ICC/IF (1:100)

45kDa

Conjugated antibodies should be stored according to the product label

For research use only.

1 μg/ml was sufficient for detection of Synaptotagmin-7 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

ICC, IF, IHC, WB

NP_061271.1

Mouse

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

IgG2B